Frank is the head of the individual differences and psychodiagnostics lab at Saarland University. His main research interests aim at understanding why people differ and become who they are, which involves behavioral genetics in the areas of personality (including self-regulation) and cognitive ability, and on a greater scheme, social inequality and life-chances. He is also active in the field of psychological test development.

In the RTG, Frank is a senior researcher of project F6.